WebMar 5, 2024 · Xiong Z, Alves CS, Wang J, et al. Zwitterion-functionalized dendrimer-entrapped gold nanoparticles for serum-enhanced gene delivery to inhibit cancer cell metastasis. Acta Biomater, 2024, 99: 320–329 ... Li J, Shen M, Shi X. Poly(amidoamine) dendrimer-gold nanohybrids in cancer gene therapy: A concise overview. ACS Appl Bio … WebFeb 28, 2024 · Materials and methods . Here, we present a novel strategy to precisely monitor drug release under magnetic stimulation. Methotrexate (MTX), an anticancer drug, was covalently functionalized onto iron–gold alloy magnetic nanoparticles (Fe–Au alloy nanoparticles or NFAs) through 2-aminoethanethiol grafting and the ability of this …
Applications of nanoparticle systems in gene delivery and gene therapy
WebJan 10, 2016 · This review summarizes the current state-of-the-art development of functionalized gold nanoparticles for cancer gene therapy. View. Show abstract. Gold nanoparticle-based theranostics: disease ... WebGold nanoparticles (GNPs) stand out as an up-and-coming agent in cancer diagnostics and treatment due to their high biocompatibility, minimal toxicity, excellent penetration … sda bocconi leadership
Gold Nanoparticles for Nucleic Acid Delivery: Molecular …
WebThe first time PEI was used in gene therapy was in 1995, and PEI has become one of the gold standards of non-viral gene delivery (Eliyahu et al. 2005, Wivel and Wilson 1998, Rosenberg et al. 1990). PEI is an angiogenic, endothelial cell-targeted gene delivery system ( Park et al. 2006 ). WebNanotechnology offers the means to target therapies directly and selectively to cancerous cells and neoplasms. With these tools, clinicians can safely and effectively deliver chemotherapy, radiotherapy, and the next generation of immuno- and gene therapies to the tumor. Futhermore, surgical resection of tumors can be guided and enhanced by way of … WebFeb 2, 2024 · The surfaces of gold nanoparticles (AuNPs) are functionalized with targeting peptides to enhance tumor cell recognition and uptake, and with fluorescently labeled antisense DNA hairpin oligonucleotides to detect AuNPs. ... Conde J, Larguinho M, Cordeiro A et al (2014) Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell … peabody opera house backstage tour