WebMar 21, 2024 · LGALS3 (Galectin 3) is a Protein Coding gene. Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.Among its related pathways are Gene expression (Transcription) and Innate Immune System.Gene Ontology (GO) annotations related to this gene include RNA binding and chemoattractant activity.An … WebJan 26, 2024 · Galectin-3 (Gal-3) regulates basic cellular functions such as cell-cell and cell-matrix interactions, growth, proliferation, differentiation, and inflammation. It is not …
Pronociceptive Roles of Schwann Cell–Derived Galectin-3 in …
WebMay 13, 2010 · GCS-100 is a galectin-3 antagonist with an acceptable human safety profile that has been demonstrated to have an antimyeloma effect in the context of bortezomib resistance. In the present study, the mechanisms of action of GCS-100 are elucidated in myeloma cell lines and primary tumor cells. WebGalectin-3 results should be interpreted with caution in patients with a history of therapeutic use of murine monoclonal antibodies (IgG) or their fragments or in those who have known autoimmune disorders. Specimens with high levels of γ-globulins (>2.5 g/dL) may cause false elevation in results. Galectin-3 results from patients with diseases ... on the ruff
Galectin-3: Inflammation Marker Foundation for …
WebGalectin-3 is a carbohydrate-binding lectin whose expression is associated with inflammatory cells including macrophages, neutrophils, and mast cells. Galectin-3 has been linked to cardiovascular physiological processes including myofibroblast proliferation, tissue repair, and cardiac remodeling in the setting of heart failure. Concentrations ... WebGalectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene. Function. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell–cell and cell–matrix interactions. Using fluorescence in–situ hybridization, the full length 90K cDNA has been localized to chromosome 17q25. WebGalectin-3 is a carbohydrate-binding lectin whose expression is associated with inflammatory cells including macrophages, neutrophils, and mast cells. Galectin-3 has … on the roxx partyband