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Consomic strain

WebFeb 27, 2024 · To assess the role of ChrY genetic variation on susceptibility to IAV infection, we studied male mice from a panel of 11 B6-ChrY consomic strains of mice using mouse-adapted Puerto Rico A/PR/8/34 H1N1 (PR8) IAV by challenging them with 5 × 10 3 egg infectious units (EIU), equivalent to ∼1 B6-LD 50.A significant overall effect of strain on … WebConsomic strains are special type of congenic strains. The differential segment between the consomic strain and its parental (progenitor) strain is represented by a whole chromosome. Consomic strains are often used …

MGI-Guidelines for Nomenclature of Mouse and Rat Strains

WebOct 19, 2024 · Utilizing a panel of 27 B6.Chr PWD consomic mice, we identified strain-specific microbiota profiles and complex relationships between host genetics, microbial constituents, and microbial-driven metabolic functions associated with differential susceptibility to EAE. In parallel, using a reductionist approach focusing on two of the … WebOct 1, 2024 · The consomic strain B6-ChrN MSM is abbreviated as CN, where N is the number of the chromosome transferred from MSM. CNC and CNT ( e.g., C13C and C13T) denote consomic strains that harbor the centromeric and … brake line for 2000 chevy silverado https://longbeckmotorcompany.com

Consomic mouse strain selection based on effect size ... - PubMed

WebNov 1, 2015 · This creates the consomic strain that shares with its host strain the same 1) genetic background (including chrY PAR, autosomes, chrX, mitochondrial DNA) and 2) pre- and postnatal maternal environment (including inoculated microbiota). WebJun 29, 2016 · Background: Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently … WebPubMed Central (PMC) hafele trash bin pull out

Identification of Genetic Determinants of the Sexual Dimorphism

Category:The genetic etiology of critical congenital heart disease

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Consomic strain

Backcrossing - Wikipedia

WebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. … WebFeb 11, 2015 · Using experimental allergic encephalomyelitis (EAE), a mouse model of MS, we evaluated genetic control of disease course among a panel of 26 consomic strains of mice inheriting chromosomes from the wild-derived PWD strain on the C57BL/6J background, which models the genetic diversity seen in human populations.

Consomic strain

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http://www.rgd.mcw.edu/nomen/rules-for-nomen.shtml WebConsomic strains, also known as chromosome substitution strains, are powerful tools for assigning polygenes that control quantitative complex traits to specific …

WebFeb 18, 2013 · Background. We have established 17 Y chromosome consomic (hereafter Y-consomic) mouse strains in an inbred DH/Sgn (hereafter DH) strain. There was a wide spectrum of variation in body weight and testis weight among the Y-consomic mouse strains [1, 2].Thus, it was expected that there were Y-linked genes associated with body … WebStrain State: Strain Type: Any closed colony coisogenic strain congenic strain consomic or chromosome substitution strain hybrid inbred strain major histocompatibility congenic minor histocompatibility congenic mutant stock mutant strain noninbred stock outbred stock recombinant congenic recombinant inbred segregating inbred unclassified wild ...

http://informatics.jax.org/silver/chapters/3-3.shtml WebMar 3, 2010 · Chromosome 13 consomic and congenic rat strains were analyzed to investigate the pattern of genomic pathway utilization involved in protection against salt …

WebConsomic strains are a variation on congenic strains in which a whole chromosome — rather than one local chromosomal region — is backcrossed from a donor strain onto a recipient background. In almost all cases, the donor chromosome is the Y. Like … Inbreeding depression will not occur when a new inbred strain is begun with two … 9.2 RECOMBINANT INBRED STRAINS 9.2.1 Overview 9.2.1.1 … J:301 Snell GD, Preliminary data on crossing-over between H-2, and Fu, Ki …

WebA consomic strain of animals is an inbred strain in which a whole chromosome – rather than one local chromosomal region – is replaced from a donor strain onto a recipient background. This is performed by marker-assisted breeding; the donor strain is backcrossed to the recipient strain for over eight generations and progeny (generally … brake line hold down clampsWebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. … brake line hold down clipsWebJun 29, 2016 · Chromosome substitution strains (CSSs, also referred to as consomic strains or lines) have been developed as a tool to identify chromosomes harboring … brake line hangers that clamp to tubing