WebFeb 27, 2024 · To assess the role of ChrY genetic variation on susceptibility to IAV infection, we studied male mice from a panel of 11 B6-ChrY consomic strains of mice using mouse-adapted Puerto Rico A/PR/8/34 H1N1 (PR8) IAV by challenging them with 5 × 10 3 egg infectious units (EIU), equivalent to ∼1 B6-LD 50.A significant overall effect of strain on … WebConsomic strains are special type of congenic strains. The differential segment between the consomic strain and its parental (progenitor) strain is represented by a whole chromosome. Consomic strains are often used …
MGI-Guidelines for Nomenclature of Mouse and Rat Strains
WebOct 19, 2024 · Utilizing a panel of 27 B6.Chr PWD consomic mice, we identified strain-specific microbiota profiles and complex relationships between host genetics, microbial constituents, and microbial-driven metabolic functions associated with differential susceptibility to EAE. In parallel, using a reductionist approach focusing on two of the … WebOct 1, 2024 · The consomic strain B6-ChrN MSM is abbreviated as CN, where N is the number of the chromosome transferred from MSM. CNC and CNT ( e.g., C13C and C13T) denote consomic strains that harbor the centromeric and … brake line for 2000 chevy silverado
Consomic mouse strain selection based on effect size ... - PubMed
WebNov 1, 2015 · This creates the consomic strain that shares with its host strain the same 1) genetic background (including chrY PAR, autosomes, chrX, mitochondrial DNA) and 2) pre- and postnatal maternal environment (including inoculated microbiota). WebJun 29, 2016 · Background: Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently … WebPubMed Central (PMC) hafele trash bin pull out