site stats

Cisdiamminedichloroplatinum

Webtrans-Platinum(II) diamminedichloride Cl2H6N2Pt+2 CID 441203 - structure, chemical names, physical and chemical properties, classification, patents, literature ... WebThree Co(III) complexes of a designed ligand PMAH that mimics the metal-binding domain of the antitumor antibiotic bleomycin (BLM) have been isolated and structurally characterized. The coordination

Formation and repair of DNA interstrand cross-links in ... - PubMed

WebA total of 26 patients with biopsy proved epidermoid carcinoma of the penis (Jackson stage III or IV) with measurable disease, no prior chemotherapy and adequate renal function … WebA comparative study was performed with a variety of human cell lines on the effects of treatments with cis-diamminedichloroplatinum (II) (cisplatin) on cell survival and the induction of unscheduled DNA synthesis. grand hyatt shenzhen hotel https://longbeckmotorcompany.com

Syntheses, structures and reactivities of designed analogues of …

Webcis-Diamminedichloroplatinum(II): effects of a representative metal coordination complex on mammalian cells Pharmacol Ther. 1984;25(3):297-326.doi: 10.1016/0163-7258(84)90003-2. Author E B Douple PMID: 6542679 DOI: 10.1016/0163-7258(84)90003-2 No abstract available Publication types WebCisplatin Cl2H6N2Pt CID 5460033 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ... WebThe thioredoxin (TRX) system, composed of nicotinamide adenine dinucleotide phosphate (reduced form), TRX, and TRX reductase (TRXR), has multiple biologic functions via thiol-mediated redox control. In this study, we investigated the relationship between intracellular TRXR levels and cellular sensitivity to cis-diamminedichloroplatinum (II) (CDDP). grand hyatt singapore wine shop

miR-3188 regulates nasopharyngeal carcinoma proliferation and ...

Category:Short-term cis-diamminedichloroplatinum(II) accumulation in

Tags:Cisdiamminedichloroplatinum

Cisdiamminedichloroplatinum

Inhibition of cis‐diamminedichloroplatinum (II)‐induced DNA …

WebSep 1, 1990 · The specific drug combination and experimental growth system for this introductory application was that of 1-β- d -arabinofuranosylcytosine (ara-C) and cisplatin with simultaneous drug exposure (1, 3, 6, 12, or 48 h) against L1210 leukemia in vitro. WebCisplatin (cisdiamminedichloroplatinum) for treatment of transitional cell carcinoma of the urinary bladder or urethra. J Vet Intern Med. May-Jun 1990;4(3):148-52.doi: 10.1111/j.1939-1676.1990.tb00888.x. Authors A S Moore 1 , A Cardona, W …

Cisdiamminedichloroplatinum

Did you know?

Web目的应用免疫组化方法观察豚鼠内耳S-100蛋白的表达。方法选用健康,Preyer’s反射正常豚鼠8只,4%多聚甲醛活体灌注后耳蜗冰冻切片,采取SP免疫组化方法进行S-100蛋白染色。结果耳蜗Corti’s器内外毛细胞,Deiter及Hensen细胞呈阳性表达,基底膜下细胞未着色,螺旋缘齿间细胞,螺旋神经节细胞间纤维,螺旋韧带及 ... Webcis-Diamminedichloroplatinum (II) - Trait. This product is a crystalline powder of bright yellow to orange yellow; Odorless. This product is soluble in dimethyl sulfoxide, slightly …

WebAbstract Murine leukemia L1210 cells, either sensitive or resistant to the toxic action of the cancer chemotherapeutic agent cis-diamminedichloroplatinum (II), have been studied … WebNov 1, 1983 · cis -Platinum, bleomycin, 5-fluorouracil, and cyclophosphamide were administered to rodent and canine models of osmotic blood-brain barrier modification to evaluate the relationship between tissue drug concentration in brain and the physiological and neuropathological effects of the drug.

WebSep 24, 2024 · Cisplatin (CDDP) is the drug of choice against different types of cancer. However, tumor cells can acquire resistance to the damage caused by cisplatin, generating genetic and epigenetic changes that lead to the generation of resistance and the activation of intrinsic resistance mechanisms in cancer cells. Among them, we can find mutations, … WebA total of 26 patients with biopsy proved epidermoid carcinoma of the penis (Jackson stage III or IV) with measurable disease, no prior chemotherapy and adequate renal function received 50 mg. per M.2 cis-diamminedichloroplatinum intravenously on days 1 …

WebCisplatin (cisplatinum, cis-diamminedichloroplatinum II, CDDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts in tumor cells. Cisplatin activates ferroptosis and induces autophagy. Solutions are best fresh-prepared. Catalog No. NC0564900 $86.10 / Each of 1 Qty Check Availability Add to cart

chinese food bournemouthWebJan 1, 1987 · Abstract. Human ovarian cancer cell lines with stable cisplatin resistance have been developed by chronic exposure of the parent cisplatin-sensitive A2780 line to increasing concentrations of cisplatin. 2780CP8 (CP8 refers to this cell line's growth in medium containing 8 µm cisplatin) has several clonal cytogenetic abnormalities but lacks … chinese food bow trailWebA docetaxel-resistant prostate cell line (PC3DR2) was subsequently established using the same method (9); resistance-associated genes in this cell line were examined in the present study through DNA microarray, western blot analysis and reverse transcription-quantitative polymerase chain reaction (RT-qPCR). chinese food bountiful utahWebA regression rate of 12% (4/33) among patients with advanced upper aerodigestive carcinomas who received an intravenous regimen of cis‐diamminedichloroplatinum, … grand hyatt singapore high tea menuWebcis-Diamminedichloroplatinum(II): effects of a representative metal coordination complex on mammalian cells Pharmacol Ther. 1984;25(3):297-326.doi: 10.1016/0163 … chinese food bow trail calgaryWebMar 1, 1979 · 1. Cisplatin is a co-ordination complex of a central platinum atom, two chlordies and two ammonia molecules in the “ cis ” position. 2. A prime mechanism of … chinese food bourbon chickenWebJul 4, 1995 · The combination of cis-diamminedichloroplatinum(II) (CDDP) and 7-ethyl-10-[4-(I -piperidino)-I -piperidino]carbonyloxycamptothecin (CPT-I I), a topoisomerase-l inhibitor, has been shown to be synergistic in vitro and clinically active against several human cancers refractory to chemotherapy. To elucidate the mechanism of the … chinese food bowness